抽象的
我们有效地检索复杂semant的能力ic knowledge meaningfully impacts our daily lives, yet the neural processes that underly successful access and transient failures in access remain only partially understood. In this fMRI study, we contrast activation during successful semantic access, unsuccessful semantic access due to transient access-failures (i.e., ‘tip-of-the-tongue’, ‘feeling-of-knowing’), and trials where the semantic knowledge was not possessed. Twenty-four human participants (14 female) were presented 240 trivia-based questions relating to person, place, object or scholastic knowledge-domains. Analyses of the recall event indicated a relatively greater role of a dorsomedial section of the prefrontal cortex in unsuccessful semantic access and relatively greater recruitment of the pars orbitalis of the inferior frontal gyrus in successful access. Successful access was also associated with increased activation in knowledge-domain selective areas. Generally, knowledge-domain selective areas showed increased responses for both preferred and non-preferred stimulus classes. The exception was place-selective regions (parahippocampal gyrus [PPA], transverse occipital sulcus [TOS], retrosplenial complex [RSC]), which were recruited during unsuccessful access attempts for all stimulus domains. Collectively, these results suggest that prefrontal semantic control systems and classical spatial-knowledge selective regions work together to locate relevant information and that access to complex knowledge results in a broad activation of semantic representation extending to regions selective for other knowledge domains.
意义陈述
我们拥有的深层事实知识的能力对我们的学术,专业和社交生活产生了有意义的影响。在这项功能磁共振成像的研究中,我们研究了与成功访问该知识以及语义访问中的瞬态失败相关的神经过程(舌头/知识感知感觉)。参与者试图回答从四个不同知识领域提取的琐事风格的常识问题。结果表明,前额叶的语义控制系统和经典的空间知识选择区域可以找到相关信息,并且访问复杂的知识会导致语义表示广泛激活,该语义表示扩展到对其他知识领域的选择性。
脚注
作者没有宣称没有竞争的财务利益。
该项目由欧洲研究委员会(ERC)的首发赠款Crask资助 - 摘要语义知识的皮质代表,根据欧盟的Horizon 2020研究与创新计划(授予协议第640594号)授予了Scott Fairhall。